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Concepts related to the origin of the genetic apparatus.Since the genetic apparatus is composed of nucleic acid and protein, the origin of the apparatus involves the origin of polyaminoacids and of polynucleotides, separately or together. Laboratory models for the origins of the separate macromolecular types are considered. The origin of their joint synthesis, believed to have been necessary at a later stage, is also discussed. Proteins and nucleic acids appear to have definite relationships with each other in three major contemporary biological systems, including chromatin, ribosomes, and the protein synthesizing system using nucleic acid templates. Stages considered in connection with the flow of information in the early evolution of the apparatus are environment, protoprotein, protein, RNA, and DNA.
Document ID
19730029515
Acquisition Source
Legacy CDMS
Document Type
Other - Collected Works
Authors
Lacey, J. C., Jr.
(Alabama, University Birmingham, Ala., United States)
Fox, S. W.
(Miami, University Coral Gables, Fla., United States)
Date Acquired
August 7, 2013
Publication Date
January 1, 1972
Subject Category
Biosciences
Accession Number
73A14317
Funding Number(s)
CONTRACT_GRANT: NGR-10-007-088
CONTRACT_GRANT: NIH-5-501-RR-05300-10
Distribution Limits
Public
Copyright
Other

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