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Contraction kinetics of ventricular muscle from hibernating and nonhibernating mammals.Temperature-dependent studies of excitability and tension-production kinetics were made on isolated trabecular strips from hibernating hamsters (HH), nonhibernating hamsters (CH), and from rats (R). The strips were electrically driven and isometric tension along with its first time derivative (dP/dt) were recorded. Excitabilities of both hamster tissues were greater than that of rat tissue from 5 to 38 C with HH greater than CH. Peak tension production followed the order of HH greater than CH greater than R at all temperatures below 24 C. Rat preparations showed an optimum peak tension production at about 31 C while HH and CH showed optima between 17 and 24 C. Times to maximal rates of tension rise showed significant variation. In this respect, the order of sensitivity to decreasing temperature was HH greater than CH greater than R.
Document ID
19730054801
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
South, F. E.
Jacobs, H. K.
(Missouri, University Columbia, Mo., United States)
Date Acquired
August 7, 2013
Publication Date
August 1, 1973
Publication Information
Publication: American Journal of Physiology
Volume: 225
Subject Category
Biosciences
Accession Number
73A39603
Funding Number(s)
CONTRACT_GRANT: NGR-26-004-025
Distribution Limits
Public
Copyright
Other

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