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Preflight studies on tolerance of pocket mice to oxygen and heat. I - Physiological studiesTests were carried out on pocket mice to ascertain their tolerance to elevated oxygen pressures alone and to a combination of hyperoxia and heat in excess of that expected during the flight of the mice on Apollo XVII. The mice withstood oxygen partial pressures up to 12 psi at normal room temperature (24 C, 75 F) over a period of 7 days. A few mice previously exposed to increased PO2 died in the course of exposure to an oxygen pressure of 10 psi or 12 psi (517 mm or 620 mm Hg) for 13 d in ambient heat of 32 C (90 F). Supplemental vitamin E and physiological saline loading given prior to exposure had no apparent protective effect. The overall conclusion was that the pocket mice which were to go on Apollo XVII could readily survive the ambient atmosphere to which they would be exposed.
Document ID
19750045522
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Leon, H. A.
Suri, K.
Mctigue, M.
Smith, J.
Cooper, W.
Miquel, J.
Ashley, W. W.
Behnke, A. R., Jr.
Saunders, J. F.
(NASA Ames Research Center Moffett Field, Calif.; NASA, Washington, D.C., United States)
Date Acquired
August 8, 2013
Publication Date
April 1, 1975
Subject Category
Life Sciences (General)
Accession Number
75A29594
Distribution Limits
Public
Copyright
Other

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