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Results of examination of the nasal mucosaThe olfactory epithelium, but not the nasal respiratory epithelium, of the four pocket mice (Perognathus longimembris) that survived their flight on Apollo XVII showed both diffuse alterations and numerous disseminated focal lesions. The olfactory mucosa of the mouse that died during flight was also affected, but to a minor degree insofar as could be determined. All this was in contrast to the normal appearance of the olfactory mucosa of the numerous control animals. A number of possible causes were considered: systemic or regional infection; inhaled particulate material (seed dust); by-products from the KO2 bed in aerosol or particulate form; gas contaminants originating in the flight package; volatile substances from the dead mouse; weightlessness; and cosmic ray particle radiation. Where feasible, studies were conducted in an effort to rule in or rule out some of these potentially causative factors. No definitive conclusions were reached as to the cause of the lesions in the flight mice.
Document ID
19750045529
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Kraft, L. M.
Vogel, F. S.
Lloyd, B.
Benton, E. V.
Cruty, M. R.
Haymaker, W.
Leon, H. A.
Billingham, J.
Turnbill, C. E.
Teas, V.
(Duke University, Durham, N.C.; San Francisco, University, San Francisco; NASA, Ames Research Center Moffett Field, Calif.; Cleveland Psychiatric Institute, Cleveland, Ohio; Chicago, University, Chicag, United States)
Date Acquired
August 8, 2013
Publication Date
April 1, 1975
Subject Category
Life Sciences (General)
Accession Number
75A29601
Distribution Limits
Public
Copyright
Other

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