NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Metabolic studies of transient tyrosinemia in premature infantsThe recently developed technique of gas chromatography-mass spectrometry supported by computer has considerably improved the analysis of physiologic fluids. This study attempted to demonstrate the value of this system in the investigation of metabolite patterns in urine in two metabolic problems of prematurity, transient tyrosinemia and late metabolic acidosis. Serial 24-hr urine specimens were analyzed in 9 infants. Transient tyrosinemia, characterized by 5- 10-fold increases over basal excretion of tyrosine, p-hydroxyphenyllactate, and p-hydroxyphenylpyruvate in urine, was noted in five of the infants. Late metabolic acidosis was seen in four infants, but bore no relation to transient tyrosinemia.
Document ID
19750058758
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Fernbach, S. A.
Summons, R. E.
Pereira, W. E.
Duffield, A. M.
(Stanford University Stanford, Calif., United States)
Date Acquired
August 8, 2013
Publication Date
January 1, 1975
Publication Information
Publication: Pediatric Research
Volume: 9
Subject Category
Life Sciences (General)
Accession Number
75A42830
Funding Number(s)
CONTRACT_GRANT: NGR-05-020-632
Distribution Limits
Public
Copyright
Other

Available Downloads

There are no available downloads for this record.
No Preview Available