NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Changes in glucose, insulin, and growth hormone levels associated with bedrestChanges in plasma glucose, insulin, and growth hormone (HGH) resulting from exposure to 56 d of bedrest were determined in five healthy young male subjects. Changes in the daily levels of these factors for each subject were expressed as the mean of six blood samples per 24-h period. The level of HGH dropped after 10 d of bedrest, then showed a 1.5-fold increase at 20 d and subsequently decreased gradually reaching levels of 2.5 mg/ml/24 h, well below pre-bedrest controls of 4.2 mg/ml/24 h, by the 54th d. In spite of a marked increase in the daily plasma insulin levels during the first 30 d of bedrest, glucose levels remained unchanged. Beyond 30 d of bedrest, insulin began decreasing toward pre-bedrest levels and glucose followed with a similar reduction to below the control levels of 75 mg/100 ml/24 h on day 54. The daily mean changes reflect a change in the amplitude of the diurnal variation. The daily peak in plasma insulin shifted progressively to the late evening during the bedrest period.
Document ID
19760054096
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Vernikos-Danellis, J.
(NASA Ames Research Center Moffett Field, CA, United States)
Leach, C. S.
(NASA Ames Research Center Moffett Field, CA, United States)
Winget, C. M.
(NASA Ames Research Center Moffett Field, CA, United States)
Goodwin, A. L.
(NASA Ames Research Center Moffett Field, CA, United States)
Rambaut, P. C.
(NASA Ames Research Center Biomedical Research Div., Moffett Field, Calif.; NASA, Johnson Space Center, Houston, Tex., United States)
Date Acquired
August 8, 2013
Publication Date
June 1, 1976
Subject Category
Aerospace Medicine
Accession Number
76A37062
Distribution Limits
Public
Copyright
Other

Available Downloads

There are no available downloads for this record.
No Preview Available