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Airborne testing of three antimotion sickness preparationsThirteen human volunteers were exposed to weekly flights in which standardized, steep turns were used to produce motion sickness. A combination of promethazine hydrochloride (25 mg) plus ephedrine sulphate (25 mg) was found to be equally as effective as the combination of 1-scopolamine hydrobromide (0.35 mg) plus d-amphetamine sulphate (5 mg). Droperidol (2.5 mg) was indistinguishable from the placebo. It was concluded that the treatment of choice for motion sickness is promethazine plus ephedrine.
Document ID
19770031786
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Johnson, W. H.
(Toronto, University Toronto, Canada)
Money, K. E.
(Defence and Civil Institute of Environmental Medicine Downsview, Ontario, Canada)
Graybiel, A.
(U.S. Naval Aerospace Medical Research Laboratories Pensacola, Fla., United States)
Date Acquired
August 9, 2013
Publication Date
November 1, 1976
Subject Category
Aerospace Medicine
Accession Number
77A14638
Funding Number(s)
CONTRACT_GRANT: NSG-7079
Distribution Limits
Public
Copyright
Other

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