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Origins of prokaryotes, eukaryotes, mitochondria, and chloroplastsA computer branching model is used to analyze cellular evolution. Attention is given to certain key amino acids and nucleotide residues (ferredoxin, 5s ribosomal RNA, and c-type cytochromes) because of their commonality over a wide variety of cell types. Each amino acid or nucleotide residue is a sequence in an inherited biological trait; and the branching method is employed to align sequences so that changes reflect substitution of one residue for another. Based on the computer analysis, the symbiotic theory of cellular evolution is considered the most probable. This theory holds that organelles, e.g., mitochondria and chloroplasts invaded larger bodies, e.g., bacteria, and combined functions to form eucaryotic cells.
Document ID
19780037965
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Schwartz, R. M.
(National Biomedical Research Foundation Washington, D.C., United States)
Dayhoff, M. O.
(Georgetown University; National Biomedical Research Foundation, Washington, D.C., United States)
Date Acquired
August 9, 2013
Publication Date
January 27, 1978
Publication Information
Publication: Science
Volume: 199
Subject Category
Space Biology
Accession Number
78A21874
Funding Number(s)
CONTRACT_GRANT: NIH-RR-05681
CONTRACT_GRANT: NIH-GM-08710
CONTRACT_GRANT: NASW-3019
Distribution Limits
Public
Copyright
Other

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