NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Erythropoietic effects of space flightVarious factors which are important in the regulation of erythropoiesis have been studied in dehydrated mice in the belief that some information would be gained relevant to the erythropoietic effects of space flight. Dehydration reduced the plasma volume and, because changes in red cell volume were minimal, the hematocrit was elevated. Thus a state of relative erythrocytosis was produced. Understanding of the mechanism whereby these changes decreased red cell production is uncertain and appears to differ somewhat from the erythroid suppression seen following elevation of the hematocrit in animals with an absolute erythrocytosis. It is suggested that factors outside of the normal erythropoietic control pathway (such as energy balance) may play an important role in the decrease in red cell volume seen in man following space flight.
Document ID
19790058180
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Dunn, C. D. R.
(Tennessee Univ. Knoxville, TN, United States)
Lange, R. D.
(Tennessee, University Knoxville, Tenn., United States)
Date Acquired
August 9, 2013
Publication Date
June 1, 1979
Publication Information
Publication: Acta Astronautica
Volume: 6
Subject Category
Life Sciences (General)
Accession Number
79A42193
Funding Number(s)
CONTRACT_GRANT: NAS9-15164
CONTRACT_GRANT: NIH-HL-10567
CONTRACT_GRANT: NIH-FR-5541
Distribution Limits
Public
Copyright
Other

Available Downloads

There are no available downloads for this record.
No Preview Available