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Simulated weightlessness - Effects on bioenergetic balanceAs a prelude to a flight experiment, an attempt was made to separate energy requirements associated with gravity from all other metabolic needs. The biological effects of weightlessness were simulated by suspending animals in a harness so that antigravity muscles were not supporting the body. Twelve pairs of rats were allowed to adapt to wearing a harness for 5 d. Experimental animals were then suspended in harness for 7 d followed by recovery for 7 d. Control animals were harnessed but never suspended. Oxygen consumption, carbon dioxide production and rate of (C-14)O2 expiration from radio-labeled glucose were monitored on selected days. Food intake and body mass were recorded daily. Metabolic rate decreased in experimental animals during 7 d of suspension and returned to normal during recovery. Although some of the metabolic changes may have related to variation in food intake, simulated weightlessness appears to directly affect bioenergetic balance.
Document ID
19800037374
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Jordan, J. P.
(Colorado State Univ. Fort Collins, CO, United States)
Sykes, H. A.
(Colorado State Univ. Fort Collins, CO, United States)
Crownover, J. C.
(Colorado State Univ. Fort Collins, CO, United States)
Schatte, C. L.
(Colorado State Univ. Fort Collins, CO, United States)
Simmons, J. B., II
(Colorado State Univ. Fort Collins, CO, United States)
Jordan, D. P.
(Colorado State University Fort Collins, Colo., United States)
Date Acquired
August 10, 2013
Publication Date
February 1, 1980
Subject Category
Life Sciences (General)
Accession Number
80A21544
Funding Number(s)
CONTRACT_GRANT: NSG-2232
Distribution Limits
Public
Copyright
Other

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