An ultrasonic plethysmograph for space flight applications

The development of an ultrasonic plethysmograph based on the transit time measurement principle is reported, which meets the space-imposed requirements for evaluating cardiovascular deconditioning. It consists of a pulse generator, pulse receiver amplifier, voltage comparator, synchronous pulse generator, elapsed time counter, and transmit and receive piezoelectric crystals resonant at 2 MHz and of 3 mm diameter. The transit time for an ultrasonic pulse to propagate across a limb cross section is computed in a digital fashion using a 32 MHz clock, and resolution is 0.049 mm with the range being approximately 200 mm. Experimental results regarding dynamic system response were found comparable in both accuracy and sensitivity to those of a Whitney strain gage using a 50 torr venous occlusion.