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Effect of simulated weightlessness on the immune system in ratsRats suspended in a model system designed to simulate many aspects of weightlessness were immunized with sheep red blood cells. Parameters measured on these and control rats included titers of anti-sheep red blood cell antibodies, serum immunoglobulin levels, spleen and thymus weights, hematocrits, and leukocyte differential counts on peripheral blood. No significant differences were found between test and weight-bearing, harnessed controls; however, the thymuses of animals in both these groups were significantly smaller than untreated cage controls. The lack of an effect of simulated weightlessness on the immune system is an interesting result, and its significance is discussed.
Document ID
19800041724
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Caren, L. D.
(NASA Ames Research Center Moffett Field, CA, United States)
Mandel, A. D.
(NASA Ames Research Center Moffett Field, CA, United States)
Nunes, J. A.
(NASA Ames Research Center Moffett Field; Santa Clara, University, Santa Clara, Calif., United States)
Date Acquired
August 10, 2013
Publication Date
March 1, 1980
Subject Category
Life Sciences (General)
Accession Number
80A25894
Funding Number(s)
CONTRACT_GRANT: NCA2-OR-685-813
Distribution Limits
Public
Copyright
Other

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