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Velocity and attenuation of sound in arterial tissuesThe velocity of sound in excised human and canine arterial tissues is measured in order to serve as a basis for the development and application of ultrasonic techniques for the diagnosis of atherosclerotic lesions. Measurements of sound velocity at different regions of 11 human and six canine aortas were made by a time delay spectrometer technique at frequencies from 2 to 10 MHz, and compared with ultrasonic attenuation parameters and the results of biochemical assays. Sound velocity is found to increase with increasing attenuation at all frequencies, and with increasing collagen content. A strong dependence of sound velocity on cholesterol content or low calcium contents is not observed, although velocities of up to 2000 m/sec are observed in highly organized calcified lesions. A decrease in velocity with decreasing temperature is also noted. It is thus concluded that it is principally the differences in tissue collagen levels that contribute to image formation according to sound velocity.
Document ID
19820048888
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Rooney, J. A.
(Maine, University Orono, ME, United States)
Gammell, P. M.
(California Institute of Technology, Jet Propulsion Laboratory, Pasadena, CA; Southern California, University Los Angeles, CA, United States)
Hestenes, J. D.
(California Institute of Technology, Jet Propulsion Laboratory, Pasadena CA, United States)
Chin, H. P.
(Maine Univ. Orono, ME, United States)
Blankenhorn, D. H.
(Southern California, University Los Angeles, CA, United States)
Date Acquired
August 10, 2013
Publication Date
February 1, 1982
Publication Information
Publication: Acoustical Society of America
Subject Category
Man/System Technology And Life Support
Accession Number
82A32423
Funding Number(s)
CONTRACT_GRANT: NIH-N01-HV-7-2930
Distribution Limits
Public
Copyright
Other

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