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Electrophoresis tests on STS-3 and ground control experiments - A basis for future biological sample selectionsStatic zone electrophoresis is an electrokinetic method of separating macromolecules and small particles. However, its application for the isolation of biological cells and concentrated protein solutions is limited by sedimentation and convection. Microgravity eliminates or reduces sedimentation, floatation, and density-driven convection arising from either Joule heating or concentration differences. The advantages of such an environment were first demonstrated in space during the Apollo 14 and 16 missions. In 1975 the Electrophoresis Technology Experiment (MA-011) was conducted during the Apollo-Soyuz Test Project flight. In 1979 a project was initiated to repeat the separations of human kidney cells. One of the major objectives of the Electrophoresis Equipment Verification Tests (EEVT) on STS-3 was to repeat and thereby validate the first successful electrophoretic separation of human kidney cells. Attention is given to the EEVT apparatus, the preflight electrophoresis, and inflight operational results.
Document ID
19820063432
Acquisition Source
Legacy CDMS
Document Type
Conference Paper
Authors
Morrison, D. R.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Lewis, M. L.
(NASA Johnson Space Center Houston, TX, United States)
Date Acquired
August 10, 2013
Publication Date
September 1, 1982
Subject Category
Astronautics (General)
Report/Patent Number
IAF PAPER 82-152
Accession Number
82A46967
Funding Number(s)
CONTRACT_GRANT: NAS9-15584
CONTRACT_GRANT: NAS9-16389
Distribution Limits
Public
Copyright
Other

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