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Human cellular immune responsiveness following space flightPeripheral circulating lymphocytes were separated from astronaut blood samples three times before and two times after the first four US Space Shuttle flights. The ability of the in vitro T lymphocytes to respond to Phytohemagglutinin by blastogenesis was found to be reduced for each crewmember following spaceflight. In addition, the astronauts experienced a postflight increase in neutrophils and a decrease in eosinophils. These postflight changes in leukocytes are shown to increase with subjectively-evaluated increases in the incidence of inflight stress, indicating that stress, and not hypogravity, is likely to be the major effector of these changes.
Document ID
19840032382
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Taylor, G. R.
(NASA Lyndon B. Johnson Space Center Houston, TX, United States)
Dardano, J. R.
(NASA Johnson Space Center Houston, TX, United States)
Date Acquired
August 12, 2013
Publication Date
December 1, 1983
Publication Information
Publication: Aviation, Space, and Environmental Medicine
Volume: 54
ISSN: 0095-0562
Subject Category
Aerospace Medicine
Accession Number
84A15169
Funding Number(s)
CONTRACT_GRANT: NAS9-15425
Distribution Limits
Public
Copyright
Other

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