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Simulating certain aspects of hypogravity - Effects on bone maturation in the nonweight bearing skeletonFor a determination of how the nonweight-bearing skeletons, i.e., lower jaws, of 41-day and 1-year old rats would respond to 10 or 14 days of partial skeletal unloading by elevating the hindquarters (PULEH), an experimental system to simulate the fluid shifts and unloading of portions of the skeleton which occur during spaceflight was developed. In comparison with the bone matrix mineralization recorded in the mandibles of rats flown in the Soviet 18.5 day Cosmos-1129 mission, the PULEH studies failed to produce spaceflight-like maturation defects.
Document ID
19840048078
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Simmons, D. J.
(California Univ. San Francisco, CA, United States)
Grazman, B.
(California Univ. San Francisco, CA, United States)
Russell, J. E.
(California Univ. San Francisco, CA, United States)
Walker, W. V.
(Washington University St. Louis, MO, United States)
Bikle, D. D.
(California, University San Francisco, CA, United States)
Morey, E. R.
(NASA Ames Research Center Biomedical Research Div., Moffett Field, CA, United States)
Date Acquired
August 12, 2013
Publication Date
December 1, 1983
Publication Information
Publication: Aviation, Space, and Environmental Medicine
Volume: 54
ISSN: 0095-0562
Subject Category
Life Sciences (General)
Accession Number
84A30865
Funding Number(s)
CONTRACT_GRANT: NAGW-236
CONTRACT_GRANT: NAGW-301
Distribution Limits
Public
Copyright
Other

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