The chemical composition of the pre-solar nebula

The chemical composition of comets may reflect an origin in the molecular cloud which subsequently formed the solar nebula. The chemistry of different types of interstellar clouds is contrasted, including an inventory of molecular species detected in Orion and in TMC 1. The first astronomical detections of the J = (1-0) transition of HCS(+) and the J = (16-15) transition of HC5N and the first detection of SO2 in a cold dust cloud are reported.