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Hypergravity effects on litter size, nursing activity, prolactin, TSH, T3, and T4 in the ratIn a recent study of the effects of hypergravity (HG) on the reproductive system of the rat, it was found that the estrous cycle is perturbed in a pseudopregnancy-like pattern upon first exposure of animals to HG. This can be prevented by previous exposure to HG or by administration of bromergo cryptin. Adapted rats can mate and deliver in HG. However, little is known of the condition of the individual pregnant rat, fetuses, and newborn pups in this environment. There are also questions regarding the effects of HG on the number of fetuses, the mortality rate in different HG levels, and the effects on production and secretion of PRL and TSH. The present investigation is concerned with such questions, taking into account possible approaches to avoid or minimize the lethal effects of HG. The obtained results suggest that peripartum plasma PRL levels and thyroid hormone levels are critical for the survival of the litter.
Document ID
19850034665
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Megory, E.
(NASA Ames Research Center Moffett Field, CA, United States)
Oyama, J.
(NASA Ames Research Center Biomedical Research Div., Moffett Field, CA, United States)
Date Acquired
August 12, 2013
Publication Date
December 1, 1984
Publication Information
Publication: Aviation, Space, and Environmental Medicine
Volume: 55
ISSN: 0095-6562
Subject Category
Life Sciences (General)
Accession Number
85A16816
Distribution Limits
Public
Copyright
Other

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