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Fatigue and contraction of slow and fast muscles in hypokinetic/hypodynamic ratsThe effects of hypokinesia/hypodynamia (H/H) on the fatigability and contractile properties of the rat soleus (S) and gastrocnemius (G) muscles have been investigated experimentally. Whole body suspension for one week was used to induce H/H, and fatigue was brought on by train stimulation for periods of 45 and 16 minutes. Following stimulation, rapid rates of fatigue were observed in the G-muscles of the suspended rats, while minimal fatigue was observed in the S-muscles. The twitch and tetanic contractile properties of the muscles were measured before and after train stimulation. It is found that H/H suspension increased twitch tension in the G-muscles, but did not change any contractile properties in the S-muscles. The peak twitch, train, tetanic tensions and time to peak were unchanged in the S-muscles of the suspended rats. On the basis of the experimental results, it is concluded that 1 wk of muscle atropy induced by H/H significantly increases fatigability in G-muscles, but does not affect the contractile properties of fast-twitch and slow-twitch muscles.
Document ID
19850038965
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Fell, R. D.
(Louisville Univ. KY, United States)
Gladden, L. B.
(Louisville Univ. KY, United States)
Steffen, J. M.
(Louisville Univ. KY, United States)
Musacchia, X. J.
(Louisville, University Louisville, KY, United States)
Date Acquired
August 12, 2013
Publication Date
January 1, 1985
Publication Information
Publication: Journal of Applied Physiology
Volume: 58
ISSN: 0161-7567
Subject Category
Life Sciences (General)
Accession Number
85A21116
Funding Number(s)
CONTRACT_GRANT: NSG-2325
Distribution Limits
Public
Copyright
Other

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