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Localization of calcium stimulated adenosine triphosphatase activity in blood vessels of the skeletonAlkaline phosphatase is an enzyme found in bone forming cells which decreases in certain bones as a result of hypogravity or non-weight bearing. This enzyme can also hydrolyze adenosine triphosphate. Therefore, an effort was made to localize calcium-stimulated ATPase by cytochemistry to determine whether altered bone cell activity might be related to changing calcium levels which occur during hypogravity. The results indicate that Ca(++)-ATPase is largely found along the endothelium and basal lamina of blood vessels, and not found in bone forming cells. This suggests that calcium regulation in the vicinity of bone formation may be modulated by the vasculature of the area.
Document ID
19860045686
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Doty, S. B.
(Columbia University New York, United States)
Date Acquired
August 12, 2013
Publication Date
December 1, 1985
Publication Information
Publication: Physiologist, Supplement
Volume: 28
ISSN: 0031-9376
Subject Category
Life Sciences (General)
Accession Number
86A30424
Funding Number(s)
CONTRACT_GRANT: NCC2-325
Distribution Limits
Public
Copyright
Other

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