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Differential partition of virulent Aeromonas salmonicida and attenuated derivatives possessing specific cell surface alterations in polymer aqueous-phase systemsTwo-polymer aqueous-phase systems in which partitioning of biological matter between the phases occurs according to surface properties such as hydrophobicity, charge, and lipid composition are used to compare the surface properties of strains of the fish pathogen Aeromonas salmonicida. The differential ability of strains to produce a surface protein array crucial to their virulence, the A layer, and to produce smooth lipopolysaccharide is found to be important in the partitioning behavior of Aeromonas salmonicida. The presence of the A layer is shown to decrease the surface hydrophilicity of the pathogen, and to increase specifically its surface affinity for fatty acid esters of polyethylene glycol. The method has application to the analysis of surface properties crucial to bacterial virulence, and to the selection of strains and mutants with specific surface characteristics.
Document ID
19870027381
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Van Alstine, J. M.
(NASA Marshall Space Flight Center Huntsville, AL; British Columbia, University, Vancouver, Canada)
Trust, T. J.
(Victoria, University Canada)
Brooks, D. E.
(British Columbia, University Vancouver, Canada)
Date Acquired
August 13, 2013
Publication Date
June 1, 1986
Publication Information
Publication: Applied and Environmental Microbiology
Volume: 51
ISSN: 0099-2240
Subject Category
Life Sciences (General)
Accession Number
87A14655
Distribution Limits
Public
Copyright
Other

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