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Estimation of left ventricular mass in conscious dogsA method for the assessment of the development or the regression of left ventricular hypertrophy (LVH) in a conscious instrumented animal is described. First, the single-slice short-axis area-length method for estimating the left-ventricular mass (LVM) and volume (LVV) was validated in 24 formaldehyde-fixed canine hearts, and a regression equation was developed that could be used in the intact animal to correct the sonomicrometrically estimated LVM. The LVM-assessment method, which uses the combined techniques of echocardiography and sonomicrometry (in conjunction with the regression equation), was shown to provide reliable and reproducible day-to-day estimates of LVM and LVV, and to be sensitive enough to detect serial changes during the development of LVH.
Document ID
19870061031
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Coleman, Bernell
(Howard Univ. Washington, DC, United States)
Cothran, Laval N.
(Howard Univ. Washington, DC, United States)
Ison-Franklin, E. L.
(Howard University Washington, DC, United States)
Hawthorne, E. W.
(Howard Univ. Washington, DC, United States)
Date Acquired
August 13, 2013
Publication Date
January 1, 1986
Publication Information
Publication: American Journal of Physiology: Heart and Circulatory Physiology
Volume: 20
ISSN: 0363-6135
Subject Category
Life Sciences (General)
Accession Number
87A48305
Funding Number(s)
CONTRACT_GRANT: NAG2-250
Distribution Limits
Public
Copyright
Other

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