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Liposomes with polyribonucleotides as model of precellular systemsThree types of liposomes were prepared under anoxic conditions: from dipalmitoyl phosphatidyl choline (DPPC), from egg yolk phosphatidyl choline (PC), and from PC with cholesterol (PC:Chol). These were used for encapsulation of poly(U) and poly(C). It was found that 36 to 70 percent of the available liposome lipids and 2 to 5 percent of the polyribonucleotides could be entrapped. An enhanced encapsulation of poly(U) and poly(C) by all three types of liposomes was observed in the presence of 0.001 to 0.01 M Zn(2+), with the effect being greatest with DPPC. The presence of 1.0 M urea inhibited the formation of PC liposomes.
Document ID
19870066561
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Baeza, Isabel
(Instituto Politecnico Nacional Mexico City, Mexico)
Ibanez, Miguel
(Instituto Politecnico Nacional Mexico City, Mexico)
Santiago, Carlos
(Instituto Politecnico Nacional Mexico City, Mexico)
Lazcano, Antonio
(Instituto Politecnico Nacional Mexico City, Mexico)
Arguello, Carlos
(Instituto Politecnico Nacional, Mexico City, Mexico)
Date Acquired
August 13, 2013
Publication Date
January 1, 1987
Publication Information
Publication: Origins of Life
Volume: 17
Issue: 3-4
ISSN: 0302-1688
Subject Category
Space Biology
Accession Number
87A53835
Funding Number(s)
CONTRACT_GRANT: NGR-44-005-002
Distribution Limits
Public
Copyright
Other

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