Renal effects of anti-gravity suit inflation in man in relation to cardiovascular and hormonal changesIt is shown that inflation for 3 hr of an antigravity suit that covered the legs and abdomen of normal standing subjects results in significant increases in urine flow, osmolar and free water clearances, total and fractional sodium excretion, and potassium excretion, while glomerular filtration rate and renal plasma flow are transiently increased. Such changes in kidney function are the consequence of the increase in thoracic blood volume induced by inflation which also results in an immediate increase in blood pressure and reflex bradycardia, together with a progressive lowering of plasma renin activity and aldosterone. The changes in kidney excretory patterns brought about by suit inflation appear to be similar in nature and magnitude to those observed during water immersion or in the early phase of bed rest, situations known to result in a headward redistribution of blood.
Document ID
19880010575
Acquisition Source
Legacy CDMS
Document Type
Conference Paper
Authors
Geelen, G. (Lyon-1 Univ. (France), United States)
Kravik, S. E. (EEG Research Inst. Oslo (Norway), United States)
Hadj-Aissa, A. (Lyon-1 Univ. (France), United States)
Vincent, M. (Lyon-1 Univ. (France), United States)
Sem-Jacobsen, C. W. (EEG Research Inst. Oslo (Norway), United States)
Greenleaf, J. (NASA Ames Research Center Moffett Field, CA., United States)
Gharib, C. (Lyon-1 Univ. France)
Date Acquired
September 5, 2013
Publication Date
December 1, 1987
Publication Information
Publication: ESA. Proceedings of the 3rd European Symposium on Life Sciences Research in Space