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Fluid control mechanisms in weightlessnessExperiments performed on Space Shuttle flights have emphasized study of the earliest effects of the cephalad fluid shift resulting from microgravity. Analysis of one subject's urine collected during flight showed that a sharp increase in antidiuretic hormone occurred within 2 h of launch, followed by an increase in cortisol excretion. Although this subject had symptoms of the space adaptation syndrome (SAS), inflight data from Spacelab missions suggested that these transient changes were not caused by SAS. Unpaired t-tests and Mann-Whitney tests showed that before and after flight, plasma thyroxine and urine osmolality were significantly higher in Shuttle crewmembers who exhibited more severe symptoms of SAS than in asymptomatic crewmembers.
Document ID
19880025737
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Leach, Carolyn S.
(NASA Johnson Space Center Houston, TX, United States)
Date Acquired
August 13, 2013
Publication Date
September 1, 1987
Publication Information
Publication: Aviation, Space, and Environmental Medicine
Volume: 58
ISSN: 0095-6562
Subject Category
Aerospace Medicine
Accession Number
88A12964
Distribution Limits
Public
Copyright
Other

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