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Problems in analysis of data from muscles of rats flow in spaceComparison of hind-limb muscles of rats flown on Spacelab-3 or tail-traction-suspended showed that 11-17 h reloading postflight might have altered the results. Soleus atrophied; plantaris, gastrocnemius, and extensor digitorum longus grew slower; and tibialis anteiror grew normally. In both flight and simulated soleus and plantaris, higher tyrosine and greater glutamine/glutamate ratio indicated negative protein balance and increased glutamine production, respectively, relative to controls. Aspartate was lower in these muscles. Reloading generally decreased tyrosine, but increased aspartate and glutamine/glutamate. These data showed that 12 h of reloading after flight is characterized by reversal, to varying extents, of the effects of unloading.
Document ID
19880066783
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Tischler, Marc E.
(Arizona Univ. Tucson, AZ, United States)
Henriksen, Erik
(Arizona Univ. Tucson, AZ, United States)
Jacob, Stephan
(Arizona Univ. Tucson, AZ, United States)
Satarug, Soisungwan
(Arizona Univ. Tucson, AZ, United States)
Cook, Paul
(Arizona, University Tucson, United States)
Date Acquired
August 13, 2013
Publication Date
February 1, 1988
Publication Information
Publication: Physiologist, Supplement
Volume: 31
ISSN: 0031-9376
Subject Category
Life Sciences (General)
Accession Number
88A54010
Funding Number(s)
CONTRACT_GRANT: NAGW-227
Distribution Limits
Public
Copyright
Other

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