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Vascular pressures and passage of gas emboli through the pulmonary circulationDoppler technique was used to measure the pulmonary vascular pressure gradients in dogs that received venous air emboli (VAE) at the rate of 0.35 ml/kg per min, at which the spillover of bubbles into the systemic arteries occur. It was found that, in 60 percent of dogs, venous bubbles spilled over into the arterial circulation at the pulmonary vascular pressure gradient of about 34.7 mm Hg. When the pulmonary vascular pressure gradient was raised to about 52 mm Hg, the spillover of venous bubbles occurred 100 percent of time. It is concluded that venous bubbles can cross the lungs of anesthetized dogs when the driving pressures are sufficient to overcome the normal filtering function.
Document ID
19890027429
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Butler, B. D.
(Texas Univ. Houston, TX, United States)
Katz, J.
(Texas, University Houston, United States)
Date Acquired
August 14, 2013
Publication Date
January 1, 1988
Publication Information
Publication: Undersea Biomedical Research
Volume: 15
Issue: 3 19
ISSN: 0093-5387
Subject Category
Life Sciences (General)
Accession Number
89A14800
Funding Number(s)
CONTRACT_GRANT: NAG9-215
Distribution Limits
Public
Copyright
Other

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