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Late cataractogenesis caused by particulate radiations and photons in long-lived mammalian speciesRadiation cataractogenesis induced by small acute doses of particulate radiations and photons in the New Zealand white rabbit (Oryctolagus cuniculus), the beagle dog (Canis familiaris) and the rhesus monkey (Macaca mulatta) is discussed in the context of the use of animal models to assess the radiation hazards faced by humans during lengthy sojourns in deep space. Attention is paid to (1) the importance of lifespan studies with long-lived species - the above animals have median lifespans in captivity of 5-7, 13-14 and 25 years, respectively; and (2) the magnitudes of possible dose thresholds for cataractogenesis from sparsely ionizing radiations and the modifications of those thresholds by the late degenerative phase of the phenomenon.
Document ID
19890066867
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Lett, J. T.
(Colorado State Univ. Fort Collins, CO, United States)
Lee, A. C.
(Colorado State University Fort Collins, United States)
Cox, A. B.
(Colorado State Univ. Fort Collins, CO, United States)
Wood, D. H.
(USAF, School of Aerospace Medicine, Brooks AFB TX, United States)
Date Acquired
August 14, 2013
Publication Date
January 1, 1989
Publication Information
Publication: - Radiation Biology, Espoo, Finland, July 18-29, 1988) Advances in Space Research
ISSN: 0273-1177
Subject Category
Life Sciences (General)
Accession Number
89A54238
Funding Number(s)
CONTRACT_GRANT: F33615-85-C-4514
CONTRACT_GRANT: NAG9-10
Distribution Limits
Public
Copyright
Other

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