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Skeletal muscle response to spaceflight, whole body suspension, and recovery in ratsThe effects of a 7-day spaceflight (SF), 7- and 14-day-long whole body suspension (WBS), and 7-day-long recovery on the muscle weight and the morphology of the soleus and the extensor digitorum longus (EDL) of rats were investigated. It was found that the effect of 7-day-long SF and WBS were highly comparable for both the soleus and the EDL, although the soleus muscle from SF rats showed greater cross-sectional area reduction than that from WBS rats. With a longer duration of WBS, there was a continued reduction in cross-sectional fast-twitch fiber area. Muscle plasticity, in terms of fiber and capillary responses, showed differences in responses of the two types of muscles, indicating that antigravity posture muscles are highly susceptible to unloading.
Document ID
19910035938
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Musacchia, X. J.
(Louisville Univ. KY, United States)
Steffen, J. M.
(Louisville Univ. KY, United States)
Fell, R. D.
(Louisville Univ. KY, United States)
Dombrowski, M. J.
(Louisville, University KY, United States)
Date Acquired
August 15, 2013
Publication Date
December 1, 1990
Publication Information
Publication: Journal of Applied Physiology
Volume: 69
ISSN: 0161-7567
Subject Category
Life Sciences (General)
Accession Number
91A20561
Funding Number(s)
CONTRACT_GRANT: NAG2-386
CONTRACT_GRANT: NASA ORDER A-21996-C
Distribution Limits
Public
Copyright
Other

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