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Carotid-cardiac baroreflex - Relaxation with orthostatic hypotension following simulated microgravity and implications for development of countermeasuresAn examination has been made of the function of the human carotid-cardiac baroreflex (CCB) under the influence of simulated microgravity, varying states of vascular volume, and acute exercise. Results have been obtained which suggest that acute fluid replacement prior to reentry may not reverse the impaired baroreflex associated with postflight hypotension. It is also noted that one bout of maximal exercise increased baroreflex sensitivity and buffer capacity through 24 hrs post exercise; these baroreflex changes were the opposite of those following head-down bedrest. Contributions of reduced blood volume and impaired CCB function to orthostatic hypotension following microgravity appear to be separate and additive, so that maximal exercise and fluid replacement could be a potent countermeasure against postflight hypotension.
Document ID
19910038805
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Convertino, Victor A.
(NASA Kennedy Space Center Cocoa Beach, FL, United States)
Date Acquired
August 15, 2013
Publication Date
January 1, 1991
Publication Information
Publication: Acta Astronautica
Volume: 23
ISSN: 0094-5765
Subject Category
Aerospace Medicine
Accession Number
91A23428
Distribution Limits
Public
Copyright
Other

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