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Training-induced alterations in young and senescent rat diaphragm muscleThe effect of progressive treadmill exercise on oxidative capacity in three specific diaphragm muscle fiber types and on the capillary density of known fiber types was investigated in young (5 month) and senescent (23 months or older) rats. All animals were trained for 1 hr/day, 5 days weekly, for 10 weeks. Measurements of succinate dehydrogenase activity showed significant increases in all three fiber types in both the young and the senescent trained animals, compared with their sedentary controls. Fiber size and capillary density were not affected by exercise or age. The results demonstrate that the senescent costal diaphragm maintains its ability to adapt to an increased metabolic demand brought about by locomotor exercises.
Document ID
19920052728
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Gosselin, Luc E.
(NASA Ames Research Center Moffett Field, CA, United States)
Betlach, Michael
(NASA Ames Research Center Moffett Field, CA, United States)
Vailas, Arthur C.
(NASA Ames Research Center Moffett Field, CA, United States)
Thomas, D. P.
(Wisconsin, University Madison; Wyoming, University, Laramie, United States)
Date Acquired
August 15, 2013
Publication Date
April 1, 1992
Publication Information
Publication: Journal of Applied Physiology
Volume: 72
Issue: 4 Ap
ISSN: 8750-7587
Subject Category
Life Sciences (General)
Accession Number
92A35352
Funding Number(s)
CONTRACT_GRANT: NAG2-568
Distribution Limits
Public
Copyright
Other

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