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Altered distribution of mitochondria in rat soleus muscle fibers after spaceflightThe effect of an exposure to microgravity on the distribution of the succinate dehydrogenase (SDH) activity throughout the soleus muscle fibers was investigated by measuring SDH activity throughout the cross section of 20-30 fibers each of the slow-twitch oxidative and fast-twitch oxidative-glycolytic types of fibers in rats exposed to 12.5 days in space aboard Cosmos 1887. It was found that, after the spaceflight, the entire regional distribution of SDH activity was significantly altered (as compared to ground controls) in the slow-twitch oxidative fibers, whereas the fast-twitch oxidative-glycolytic fibers from muscles of flown rats exhibited a significantly lower SDH activity only in their subsarcolemmal region.
Document ID
19920071924
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Bell, Gordon J.
(NASA Ames Research Center Moffett Field, CA, United States)
Martin, Thomas P.
(Alberta, University Edmonton, Canada)
Il'ina-Kakueva, E. I.
(NASA Ames Research Center Moffett Field, CA, United States)
Oganov, V. S.
(Institute of Biomedical Problems Moscow, Russia)
Edgerton, V. R.
(California, University Los Angeles, United States)
Date Acquired
August 15, 2013
Publication Date
August 1, 1992
Publication Information
Publication: Journal of Applied Physiology
Volume: 73
Issue: 2 Au
ISSN: 8750-7587
Subject Category
Life Sciences (General)
Accession Number
92A54548
Funding Number(s)
CONTRACT_GRANT: NCA2-IR-390-502
Distribution Limits
Public
Copyright
Other

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