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Attenuation of human carotid-cardiac vagal baroreflex responses after physical detrainingAstronauts who are occupied with prelaunch schedules may have to limit their regular physical exercise routines. To assess a potential effect on blood pressure control, carotid baroreceptor-cardiac reflex responses of 16 men were evaluated before and after two weeks of exercise detraining that followed ten weeks of regular scheduled exercise (30 min/d, 4 d/week at 75 percent V(O2) max). After detraining, the baroreflex stimulus-response relationship had a reduced slope 0.4 msec/mmHg and range of response. In addition, there was a resetting of the relationship on the R-R interval axis. Both the minimum and maximum R-R interval responses to the stimulus were significantly reduced after detraining. Baseline systolic pressure did not change with detraining, and the carotid baroreceptor-cardiac response relationship did not shift on the pressure axis. These results suggest that detraining from regular exercise can compromise vagally-mediated mechanisms of blood pressure regulation.
Document ID
19920072104
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Convertino, Victor A.
(NASA Kennedy Space Center Cocoa Beach, FL, United States)
Fritsch, Janice M.
(NASA Johnson Space Center Houston, TX, United States)
Date Acquired
August 15, 2013
Publication Date
September 1, 1992
Publication Information
Publication: Aviation, Space, and Environmental Medicine
Volume: 63
Issue: 9, Se
ISSN: 0095-6562
Subject Category
Aerospace Medicine
Accession Number
92A54728
Distribution Limits
Public
Copyright
Other

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