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Rodent growth, behavior, and physiology resulting from flight on the Space Life Sciences-1 missionA rodent-based spaceflight study is conducted to investigate physiological changes in rats vs humans and the effects of changes in the design of the Research Animal Holding Facility (RAHF) and the Animal Enclosure Module (AEM). Rats were housed in the AEM and the RAHF, and controls were kept in identical flight hardware on earth subjected to the same flight-environmental profile. Biosamples and organ weights are taken to compare the rats before and after flight, and food/water intake are also compared. Weight gain, body weight, and food consumptions in the flight rats are significantly lower than corresponding values for the control subjects. Flight rats tend to have smaller postexperiment spleens and hearts, and flight rats consumed more water in the AEM than in the RAHF. The rodents' behavior is analogous to humans with respect to physiological and reconditioning effects, showing that the rat is a good model for basic research into the effects of spaceflight on humans.
Document ID
19920073082
Acquisition Source
Legacy CDMS
Document Type
Conference Paper
Authors
Jahns, G.
(NASA Ames Research Center Moffett Field, CA, United States)
Meylor, J.
(NASA Ames Research Center Moffett Field, CA, United States)
Fast, T.
(NASA Ames Research Center Moffett Field, CA, United States)
Hawes, N.
(Lockheed Engineering & Sciences Co.; NASA, Ames Research Center Moffett Field, CA, United States)
Zarow, G.
(USVA, Medical Center San Francisco, CA, United States)
Date Acquired
August 15, 2013
Publication Date
August 1, 1992
Subject Category
Life Sciences (General)
Report/Patent Number
IAF PAPER 92-0268
Accession Number
92A55706
Distribution Limits
Public
Copyright
Other

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