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Imaging Genetic Molecules At Atomic ResolutionProposed method of imaging informational polymeric biological molecules at atomic resolution enables determination of sequences of component monomers about 10 to the 3rd power to 10 to the 4th power times as fast as conventional methods do. Accelerates research on genetic structures of animals and plants. Also contributes significantly to imaging processes like scanning electron microscopy (SEM), atomic-force microscopy (AFM), and scanning tunneling microscopy (STM) in cases in which necessary to locate or identify small specimens on relatively large backgrounds and subtract background images to obtain images of specimens in isolation. V-grooves on silicon wafer laid out in square pattern, intersections of which marked to identify coordinates. Specimen molecules held in grooves for reproducible positioning and scanning by AFM or STM.
Document ID
19930000684
Acquisition Source
Legacy CDMS
Document Type
Other - NASA Tech Brief
Authors
Coles, L. Stephen
(Caltech)
Date Acquired
August 16, 2013
Publication Date
October 1, 1993
Publication Information
Publication: NASA Tech Briefs
Volume: 17
Issue: 10
ISSN: 0145-319X
Subject Category
Life Sciences
Report/Patent Number
NPO-18563
Accession Number
93B10684
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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