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Cardiovascular adaptation to spaceflightData are presented on the rate of adaptation of the human cardiovascular system to conditions of spaceflight, with particular attention given to data obtained during spaceflight in the U.S. Space Shuttle Program. It is pointed out that many of the cardiovascular changes that occurred during spaceflights that lasted from 2 to 11 days can be traced directly to changes in the body fluid volume. The beneficial effects of a fluid loading countermeasure (oral rehydration) and of the supine body position on the heart rate during the spaceflight are demonstrated. It is noted that, after hours or a few days of spaceflight, a state of adaptation is reached, in which the subject is well adapted and appropriately hydrated for the weightless environment. However, the return to the normal gravity of the earth leaves the individual especially sensitive to orthostatic stress.
Document ID
19930033553
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Charles, John B.
(NASA Johnson Space Center Houston, TX, United States)
Lathers, Claire M.
(NASA Johnson Space Center Houston, TX; Food and Drug Administration, Rockville, MD, United States)
Date Acquired
August 15, 2013
Publication Date
October 1, 1991
Publication Information
Publication: Journal of Clinical Pharmacology
Volume: 31
Issue: 10
ISSN: 0091-2700
Subject Category
Aerospace Medicine
Accession Number
93A17550
Distribution Limits
Public
Copyright
Other

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