NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Eccentric exercise training as a countermeasure to non-weight-bearing soleus muscle atrophyThis investigation tested whether eccentric resistance training could prevent soleus muscle atrophy during non-weight bearing. Adult female rats were randomly assigned to either weight bearing +/- intramuscular electrodes or non-weight bearing +/- intramuscular electrodes groups. Electrically stimulated maximal eccentric contractions were performed on anesthetized animals at 48-h intervals during the 10-day experiment. Non-weight bearing significantly reduced soleus muscle wet weight (28-31 percent) and noncollagenous protein content (30-31 percent) compared with controls. Eccentric exercise training during non-weight bearing attenuated but did not prevent the loss of soleus muscle wet weight and noncollagenous protein by 77 and 44 percent, respectively. The potential of eccentric exercise training as an effective and highly efficient counter-measure to non-weight-bearing atrophy is demonstrated in the 44 percent attenuation of soleus muscle noncollagenous protein loss by eccentric exercise during only 0.035 percent of the total non-weight-bearing time period.
Document ID
19930036036
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Kirby, Christopher R.
(NASA Ames Research Center Moffett Field, CA, United States)
Ryan, Mirelle J.
(NASA Ames Research Center Moffett Field, CA, United States)
Booth, Frank W.
(Texas Univ. Houston, United States)
Date Acquired
August 15, 2013
Publication Date
November 1, 1992
Publication Information
Publication: Journal of Applied Physiology
Volume: 73
Issue: 5
ISSN: 8750-7587
Subject Category
Life Sciences (General)
Accession Number
93A20033
Funding Number(s)
CONTRACT_GRANT: NAG2-239
CONTRACT_GRANT: NAGW-70
Distribution Limits
Public
Copyright
Other

Available Downloads

There are no available downloads for this record.
No Preview Available