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Caenorhabditis elegans - A model system for space biology studiesThe utility of the nematode Caenorhabditis elegans in studies spanning aspects of development, aging, and radiobiology is reviewed. These topics are interrelated via cellular and DNA repair processes especially in the context of oxidative stress and free-radical metabolism. The relevance of these research topics to problems in space biology is discussed and properties of the space environment are outlined. Exposure to the space-flight environment can induce rapid changes in living systems that are similar to changes occurring during aging; manipulation of these environmental parameters may represent an experimental strategy for studies of development and senescence. The current and future opportunities for such space-flight experimentation are presented.
Document ID
19930036668
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Johnson, Thomas E.
(Colorado Univ. Boulder, United States)
Nelson, Gregory A.
(JPL Pasadena, CA, United States)
Date Acquired
August 15, 2013
Publication Date
January 1, 1991
Publication Information
Publication: Experimental Gerontology
Volume: 26
Issue: 3-Feb
ISSN: 0531-5565
Subject Category
Life Sciences (General)
Accession Number
93A20665
Funding Number(s)
CONTRACT_GRANT: NIH-R01-AG-08322
CONTRACT_GRANT: NIH-K04-AG-00369
Distribution Limits
Public
Copyright
Other

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