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Insights into Ventilatory Inhomogeneity from Respiratory Measurements on Spacelab Mission D-2The relative contributions of inter-regional and intra-regional ventilation inhomogeneities of Spacelab astronauts are studied. The classical theory of ventilation distribution in the lung is that the top-to-bottom (inter-regional) ventilation inhomogeneities are primarily gravity dependent, whereas the peripheral (intra-regional) ventilation distribution is gravity independent. Argon rebreathing tests showed that gravity independent specific ventilation (ventilation per unit volume) inhomogeneities are at least as large as gravity dependent ones. Single breath tests with helium and sulfur hexafluoride showed the different sensitivity of these gases to microgravity.
Document ID
19970016691
Acquisition Source
Johnson Space Center
Document Type
Conference Paper
Authors
Paiva, Manuel
(Free Univ. Brussels, Belgium)
Verbanck, Sylvia
(Vrije Univ. Brussels, Belgium)
Linnarsson, Dag
(Karolinska Inst. Stockholm, Sweden)
Prisk, Kim
(California Univ., San Diego La Jolla, CA United States)
West, John B.
(California Univ., San Diego La Jolla, CA United States)
Date Acquired
August 17, 2013
Publication Date
October 1, 1996
Subject Category
Aerospace Medicine
Accession Number
97N19132
Funding Number(s)
CONTRACT_GRANT: NAS9-17884
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
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