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Intrinsic Kinetics Fluctuations as Cause of Growth Inhomogeneity in Protein CrystalsIntrinsic kinetics instabilities in the form of growth step bunching during the crystallization of the protein lysozyme from solution were characterized by in situ high-resolution optical interferometry. Compositional variations (striations) in the crystal, which potentially decrease its utility, e.g., for molecular structure studies by diffraction methods, were visualized by polarized light reflection microscopy. A spatiotemporal correlation was established between the sequence of moving step bunches and the striations.
Document ID
19990042333
Acquisition Source
Marshall Space Flight Center
Document Type
Reprint (Version printed in journal)
Authors
Vekilov, Peter G.
(Alabama Univ. Huntsville, AL United States)
Rosenberger, Franz
(Alabama Univ. Huntsville, AL United States)
Date Acquired
August 19, 2013
Publication Date
June 1, 1998
Publication Information
Publication: Physical Review E
Publisher: American Physical Society
Volume: 57
Issue: 6
ISSN: 1063-651X
Subject Category
Solid-State Physics
Funding Number(s)
CONTRACT_GRANT: NAG8-1168
CONTRACT_GRANT: NAG8-1161
CONTRACT_GRANT: NAG8-950
Distribution Limits
Public
Copyright
Other

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