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The Application of a Massively Parallel Computer to the Simulation of Electrical Wave Propagation Phenomena in the Heart Muscle Using Simplified ModelsThe simulation of heart arrhythmia and fibrillation are very important and challenging tasks. The solution of these problems using sophisticated mathematical models is beyond the capabilities of modern super computers. To overcome these difficulties it is proposed to break the whole simulation problem into two tightly coupled stages: generation of the action potential using sophisticated models. and propagation of the action potential using simplified models. The well known simplified models are compared and modified to bring the rate of depolarization and action potential duration restitution closer to reality. The modified method of lines is used to parallelize the computational process. The conditions for the appearance of 2D spiral waves after the application of a premature beat and the subsequent traveling of the spiral wave inside the simulated tissue are studied.
Document ID
19990109142
Acquisition Source
Armstrong Flight Research Center
Document Type
Other
Authors
Karpoukhin, Mikhii G.
(California Univ. Los Angeles, CA United States)
Kogan, Boris Y.
(California Univ. Los Angeles, CA United States)
Karplus, Walter J.
(California Univ. Los Angeles, CA United States)
Date Acquired
August 19, 2013
Publication Date
January 1, 1995
Publication Information
ISSN: 1060-3425
Subject Category
Aerospace Medicine
Meeting Information
Meeting: System Sciences
Location: HI
Country: United States
Start Date: January 1, 1995
Sponsors: Institute of Electrical and Electronics Engineers
Funding Number(s)
CONTRACT_GRANT: NSF BBS-87-14206
CONTRACT_GRANT: NCC2-374
Distribution Limits
Public
Copyright
Other

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