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Aspects of the Development of Housing for the Spaceflight of Pregnant and Lactating Rats with NeonatesRecent and upcoming spaceflights are investigating the effect of weightlessness on developing neural and organ systems. Pregnant rats and dams with neonates have to be accommodated in cages that support the special requirements of these animals. Extensive ground testing of cage concepts, the effect of launch and landing stresses on the maintenance of pregnancy and maternal behavior at different neonatal ages, and techniques for monitoring adaptability to change are discussed. A spaceflight opportunity for the NlH.R3 payload of rat families at three different postnatal ages demonstrated that the survival of very young animals was not good but that older newborns could be returned to Earth in reasonably good health. The development of cages for the Research Animal Holding Facility (RAHF) to support the flight of neonates on Neurolab was continued and incorporated modifications that were demonstrated by the NIH.R3 flight. Other modifications to the RAHF are discussed. Data from biocompatibility and experiment verification testing are presented.
Document ID
20020040907
Acquisition Source
Ames Research Center
Document Type
Conference Paper
Authors
Hinds, William E.
(NASA Ames Research Center Moffett Field, CA United States)
Mayer, David J.
(NASA Ames Research Center Moffett Field, CA United States)
Evans, Juli
(NASA Ames Research Center Moffett Field, CA United States)
Spratt, Shahn
(Lockheed Martin Engineering and Sciences Co. United States)
Lane, Philip K.
(Lockheed Martin Engineering and Sciences Co. United States)
Rodriguez, Shari L.
(Lockheed Martin Engineering and Sciences Co. United States)
Navidi, Meena
(Lockheed Martin Engineering and Sciences Co. United States)
Armstrong, Rachel
(Bionetics Corp. Moffett Field, CA United States)
Lemos, Bonnie
(Bionetics Corp. Moffett Field, CA United States)
Dalton, Bonnie P.
Date Acquired
August 20, 2013
Publication Date
January 1, 1996
Subject Category
Life Sciences (General)
Meeting Information
Meeting: 27th International Conference on Environmental Systems
Location: Lake Tahoe, NV
Country: United States
Start Date: July 14, 1997
End Date: July 17, 1997
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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