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Development of a Supported Emulsion Liquid Membrane System for Propionic Acid Separation in a Microgravity EnvironmentPerstractive fermentation is a good way to increase the productivity of bioreactors. Using Propionibacteria as the model system, the feasibility of using supported emulsion liquid membrane (SELM) for perstractive fermentation is assessed in this study. Five industrial solvents were considered as the solvent for preparing the SELM. The more polar a solvent is, the higher the partition coefficient. However, toxicity of a solvent also increases with its polarity. CO-1055 (industrial decanol/octanol blend) has the highest partition coefficient toward propionic acid among the solvents that has no molecular toxicity toward Propionibacteria. A preliminary extraction study was conducted using tetradecane as solvent in a hydrophobic hollow fiber contactor. The result confirmed that SELM eliminates the equilibrium limitation of conventional liquid-liquid extraction, and allows the use of a non-toxic solvent with low partition coefficient.
Document ID
20030016583
Acquisition Source
Marshall Space Flight Center
Document Type
Reprint (Version printed in journal)
Authors
Li, Jin
(Iowa Univ. Iowa City, IA United States)
Hu, Shih-Yao B.
(Iowa Univ. Iowa City, IA United States)
Wiencek, John M.
(Iowa Univ. Iowa City, IA United States)
Date Acquired
August 21, 2013
Publication Date
January 1, 2001
Publication Information
Publication: Biotechnol. Bioprocess Eng.
Volume: 6
Issue: 6
Subject Category
Inorganic, Organic And Physical Chemistry
Funding Number(s)
CONTRACT_GRANT: NAG8-1588
Distribution Limits
Public
Copyright
Other

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