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The immune system in space and microgravitySpace flight and models that created conditions similar to those that occur during space flight have been shown to affect a variety of immunological responses. These have primarily been cell-mediated immune responses including leukocyte proliferation, cytokine production, and leukocyte subset distribution. The mechanisms and biomedical consequences of these changes remain to be established. Among the possible causes of space flight-induced alterations in immune responses are exposure to microgravity, exposure to stress, exposure to radiation, and many more as yet undetermined causes. This review chronicles the known effects of space flight on the immune system and explores the possible role of stress in contributing to these changes.
Document ID
20040087945
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Sonnenfeld, Gerald
(Morehouse School of Medicine 720 Westview Drive, S.W., Atlanta, GA 30310-1495, United States)
Date Acquired
August 21, 2013
Publication Date
December 1, 2002
Publication Information
Publication: Medicine and science in sports and exercise
Volume: 34
Issue: 12
ISSN: 0195-9131
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Other
Keywords
unmanned
Cosmos Project
NASA Discipline Regulatory Physiology
manned
short duration
Review
STS Shuttle Project
Review, Tutorial
Non-NASA Center
Flight Experiment

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