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Effect of spaceflight on isoflavonoid accumulation in etiolated soybean seedlingsIn order to explore the potential impact of microgravity on flavonoid biosynthesis, we examined isoflavonoid levels in soybean (Glycine max) tissues generated under both spaceflight and clinorotation conditions. A 6-day Space Shuttle-based microgravity exposure resulted in enhanced accumulation of isoflavone glycosides (daidzin, 6"-O-malonyl-7-O-glucosyl daidzein, genistin, 6"-O-malonyl-7-O-glucosyl genistein) in hypocotyl and root tissues, but reduced levels in cotyledons (relative to 1g controls on Earth). Soybean seedlings grown on a horizontally rotating clinostat for 3, 4 and 5 days exhibited (relative to a vertical clinorotation control) an isoflavonoid accumulation pattern similar to the space-grown tissues. Elevated isoflavonoid levels attributable to the clinorotation treatment were transient, with the greatest increase observed in the three-day-treated tissues and smaller increases in the four- and five-day-treated tissues. Differences between stresses presented by spaceflight and clinorotation and the resulting biochemical adaptations are discussed, as is whether the increase in isoflavonoid concentrations were due to differential rates of development under the "gravity" treatments employed. Results suggest that spaceflight exposure does not impair isoflavonoid accumulation in developing soybean tissues and that isoflavonoids respond positively to microgravity as a biochemical strategy of adaptation.
Document ID
20040088064
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Levine, L. H.
(NASA Kennedy Space Center Cocoa Beach FL United States)
Levine, H. G.
Stryjewski, E. C.
Prima, V.
Piastuch, W. C.
Sager, J. S.
Date Acquired
August 21, 2013
Publication Date
December 1, 2001
Publication Information
Publication: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology
Volume: 8
Issue: 2
ISSN: 1077-9248
Subject Category
Life Sciences (General)
Funding Number(s)
CONTRACT_GRANT: NAS10-12180
Distribution Limits
Public
Copyright
Other
Keywords
Flight Experiment
NASA Center KSC
STS-87 Shuttle Project
short duration
manned
NASA Discipline Life Support Systems

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