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Research activities at the Loma Linda University and Proton Treatment Facility--an overviewThe Loma Linda University (LLU) Radiobiology Program coordinates basic research and proton beam service activities for the university and extramural communities. The current focus of the program is on the biological and physical properties of protons and the operation of radiobiology facilities for NASA-sponsored projects. The current accelerator, supporting facilities and operations are described along with a brief review of extramural research projects supported by the program. These include space craft electronic parts and shielding testing as well as tumorigenesis and animal behavior experiments. An overview of research projects currently underway at LLU is also described. These include: 1) acute responses of the C57Bl/6 mouse immune system, 2) modulation of gene expression in the nematode C. elegans and rat thyroid cells, 3) quantitation of dose tolerance in rat CNS microvasculature, 4) behavioral screening of whole body proton and iron ion-irradiated C57Bl/6 mice, and 5) investigation of the role of cell integration into epithelial structures on responses to radiation.
Document ID
20040088564
Acquisition Source
Johnson Space Center
Document Type
Reprint (Version printed in journal)
Authors
Nelson, G. A.
(Loma Linda University Radiobiology Program, Loma Linda University Loma Linda, California 92354, United States)
Green, L. M.
Gridley, D. S.
Archambeau, J. O.
Slater, J. M.
Date Acquired
August 21, 2013
Publication Date
January 1, 2001
Publication Information
Publication: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Volume: 17 Suppl 1
ISSN: 1120-1797
Subject Category
Life Sciences (General)
Funding Number(s)
CONTRACT_GRANT: NCC9-79
Distribution Limits
Public
Copyright
Other
Keywords
Non-NASA Center
NASA Discipline Radiation Health

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