NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Thermal dependence of neural activity in the hamster hippocampal slice preparation1. Neural activity was recorded in an in vitro hamster hippocampal slice preparation while the temperature of the Ringer's solution bathing in the slice was controlled at selected levels. 2. The amplitude of the population spike (action potentials from a group of pyramidal cells) was measured as bath temperature was lowered from 35 degrees C to temperatures where a response could not be evoked. 3. Plots of population spike amplitude versus temperature have bell-shaped curves. The population spikes increased in amplitude as temperature was lowered from 35 degrees C, reached a peak amplitude between 25 and 20 degrees C, and then decreased until a response could not be evoked when temperature was further lowered. 4. These in vitro results obtained in the slice preparation are related to in vivo hippocampal studies. Results are interpreted as consistent with the proposal reviewed here that neural activity in the hippocampus plays a role at specific stages of entrance into and arousal from hibernation.
Document ID
20040089617
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Horowitz, J. M.
(University of California Davis 95616, United States)
Thomas, M. P.
Eckerman, P.
Date Acquired
August 21, 2013
Publication Date
January 1, 1987
Publication Information
Publication: Journal of thermal biology
Volume: 12
Issue: 2
ISSN: 0306-4565
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Other
Keywords
Non-NASA Center
NASA Discipline Number 40-30
NASA Program Space Biology
NASA Discipline Neuroscience

Available Downloads

There are no available downloads for this record.
No Preview Available