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Incorporating biologically based models into assessments of risk from chemical contaminantsThe general approach to assessment of risk from chemical contaminants in drinking water involves three steps: hazard identification, exposure assessment, and dose-response assessment. Traditionally, the risks to humans associated with different levels of a chemical have been derived from the toxic responses observed in animals. It is becoming increasingly clear, however, that further information is needed if risks to humans are to be assessed accurately. Biologically based models help clarify the dose-response relationship and reduce uncertainty.
Document ID
20040090198
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Bull, R. J.
(College of Pharmacy, Washington State University Pullman 99163)
Conolly, R. B.
De Marini, D. M.
MacPhail, R. C.
Ohanian, E. V.
Swenberg, J. A.
Date Acquired
August 21, 2013
Publication Date
March 1, 1993
Publication Information
Publication: Journal - American Water Works Association
Volume: 85
Issue: 3
ISSN: 0003-150X
Subject Category
Environment Pollution
Distribution Limits
Public
Copyright
Other
Keywords
Review, Tutorial
Non-NASA Center
Review
NASA Program Environmental Health
NASA Discipline Number 04-10
NASA Discipline Environmental Health

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