NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Growth Modes and Energetics of 101 Face Lysozyme Crystal GrowthFrom analyses of lysozyme 101 face growth rate data using a 2D nucleation model for layer-by-layer growth, we find the effective barrier for crystal growth to be gamma = 1.0 +/- 0.2 x 10(exp -13) erg/molecule. The magnitude of the effective barrier is 2.4 +/- 0.5 k(sub beta)T, at 22 C. We also find that beyond a critical solution supersaturation, sigma(sub c), crystal growth rates are more accurately described by a kinetic roughening hypothesis. Beyond sigma(sub c), crystals grow by the continuous addition of molecules anywhere on the crystal surface rather than layer-by-layer. The magnitude of the critical supersaturation (sigma(sub c), = 1.7 +/- 0.2) for a crossover from a layer-by-layer to continuous growth is found to be statistically independent of the solution conditions that vary with buffer pH, temperature or precipitant concentration. Using the experimentally determined values for gamma and sigma(sub c), we find the crystal growth unit to be comprised of 7 +/- 3 molecules. The energy barrier, E(sub c), for the continuous addition of the growth Units is 6.2 +/- 0.3 x 10(exp -13) erg/molecule or 15 +/1 1 k(sub beta)T at 22C.
Document ID
20040121206
Acquisition Source
Marshall Space Flight Center
Document Type
Preprint (Draft being sent to journal)
Authors
Gorti, Sridhar
(NASA Marshall Space Flight Center Huntsville, AL, United States)
Forsythe, Elizabeth L.
(BAE Systems Analytical Solutions, Inc. Huntsville, AL, United States)
Pusey, L.
(NASA Marshall Space Flight Center Huntsville, AL, United States)
Date Acquired
August 22, 2013
Publication Date
January 1, 2004
Subject Category
Chemistry And Materials (General)
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

Available Downloads

There are no available downloads for this record.
No Preview Available