NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Nanopores and nucleic acids: prospects for ultrarapid sequencingDNA and RNA molecules can be detected as they are driven through a nanopore by an applied electric field at rates ranging from several hundred microseconds to a few milliseconds per molecule. The nanopore can rapidly discriminate between pyrimidine and purine segments along a single-stranded nucleic acid molecule. Nanopore detection and characterization of single molecules represents a new method for directly reading information encoded in linear polymers. If single-nucleotide resolution can be achieved, it is possible that nucleic acid sequences can be determined at rates exceeding a thousand bases per second.
Document ID
20040141625
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Deamer, D. W.
(University of California Santa Cruz, CA 95064, United States)
Akeson, M.
Date Acquired
August 22, 2013
Publication Date
April 1, 2000
Publication Information
Publication: Trends in biotechnology
Volume: 18
Issue: 4
ISSN: 0167-7799
Subject Category
Exobiology
Distribution Limits
Public
Copyright
Other
Keywords
Review
Review, Tutorial
Non-NASA Center
NASA Discipline Exobiology

Available Downloads

There are no available downloads for this record.
No Preview Available